Reply to Israel Carmi (2002): “Are the 14C Dates of the Dead Sea Scrolls Affected by Castor Oil Contamination?”

The Radiocarbon archives are made available by Radiocarbon and the University of Arizona Libraries. Contact [email protected] for further information.Migrated from OJS platform February 202

Transmission dynamics and prospects for the elimination of canine rabies

Rabies has been eliminated from domestic dog populations in Western Europe and North America, but continues to kill many thousands of people throughout Africa and Asia every year. A quantitative understanding of transmission dynamics in domestic dog populations provides critical information to assess whether global elimination of canine rabies is possible. We report extensive observations of individual rabid animals in Tanzania and generate a uniquely detailed analysis of transmission biology, which explains important epidemiological features, including the level of variation in epidemic trajectories. We found that the basic reproductive number for rabies, R<sub>0</sub>, is very low in our study area in rural Africa (∼1.2) and throughout its historic global range (<2). This finding provides strong support for the feasibility of controlling endemic canine rabies by vaccination, even near wildlife areas with large wild carnivore populations. However, we show that rapid turnover of domestic dog populations has been a major obstacle to successful control in developing countries, thus regular pulse vaccinations will be required to maintain population-level immunity between campaigns. Nonetheless our analyses suggest that with sustained, international commitment, global elimination of rabies from domestic dog populations, the most dangerous vector to humans, is a realistic goal

Electron-ion Recombination In Gas Mixtures Of Helium, Nitrogen, And Carbon Dioxide

A study has been conducted to determine the electron-ion recombination rates in gas mixtures of helium, nitrogen, and carbon dioxide. Measurements were made as functions of electric field strength, gas pressure, and gas composition. In gas mixtures containing only nitrogen and carbon dioxide, the rates were dependent on pressure. This dependence is interpreted as being due to the separate effects of two- and three-body recombination processes. No pressure dependence was observed for mixtures containing helium. In such mixtures, two-body recombination appears to be dominant. Moreover, the addition of relatively low concentrations of helium to the discharge leads to a dramatic change in the bulk recombination rate. Two possible explanations for this observation are suggested. © 1984 American Institute of Physics

Two- And Three-body Electron-ion Recombination In Carbon Dioxide

The electron-ion recombination rate in carbon dioxide was measured as a function of electric field strength and gas pressure. The separate effects of two- and three-body recombination was observed, and the respective rate constants obtained. The results indicate that three-body recombination is dominant at low field strengths for gas pressures above 1 atm, whereas two-body recombination is dominant at high field strengths

A case-only approach for assessing gene-sex interaction in human longevity

As one aspect of the complex feature of longevity, gene-sex interaction plays an important role in influencing human life span. With advances in molecular genetics, more studies aimed at assessing gene-sex interaction are expected. New and valid statistical methods are needed. In this paper, we introduce a nontraditional approach, the case-only design, which was originally proposed for assessing gene and disease associations, to detect gene-sex interaction in human longevity. Applications of this method to data collected from centenarian studies show that it can produce consistent results as compared with results obtained from case-control and other approaches. Important features of the application in human longevity studies are highlighted and discussed. Since centenarians constitute a special population representing successful ageing, the easily applicable case-only approach will be an important tool for screening potential major genes that contribute to human longevity. (AUTHORS)

Optimal concentrations in transport systems

Many biological and man-made systems rely on transport systems for the distribution of material, for example matter and energy. Material transfer in these systems is determined by the flow rate and the concentration of material. While the most concentrated solutions offer the greatest potential in terms of material transfer, impedance typically increases with concentration, thus making them the most difficult to transport. We develop a general framework for describing systems for which impedance increases with concentration, and consider material flow in four different natural systems: blood flow in vertebrates, sugar transport in vascular plants and two modes of nectar drinking in birds and insects. The model provides a simple method for determining the optimum concentration c[subscript opt] in these systems. The model further suggests that the impedance at the optimum concentration μ[subscript opt] may be expressed in terms of the impedance of the pure (c = 0) carrier medium μ[subscript 0] as μ[subscript opt]∼2[superscript α]μ[subscript 0], where the power α is prescribed by the specific flow constraints, for example constant pressure for blood flow (α = 1) or constant work rate for certain nectar-drinking insects (α = 6). Comparing the model predictions with experimental data from more than 100 animal and plant species, we find that the simple model rationalizes the observed concentrations and impedances. The model provides a universal framework for studying flows impeded by concentration, and yields insight into optimization in engineered systems, such as traffic flow.National Science Foundation (U.S.) (Grant 1021779)National Science Foundation (U.S.) (Grant DMS-0907955)National Science Foundation (U.S.). Materials Research Science and Engineering Centers (Program) (Grant DMR-0820484

Electron Drift Velocities In Gas Mixtures Of He, N2, And CO 2

An electron swarm experiment has been used to obtain electron drift velocities in the He:CO2:N2 mixtures 0:1:1, 3:1:2, and 3:1:1. The E/N range of 3 to 57 Td was studied with total gas pressure varied from 50 to 200 Torr. These particular mixtures have not been previously studied experimentally. Good agreement is observed between theoretical calculations and experimental data

Electron Drift Velocities In Xenon

The electron drift velocity has been measured in xenon over the range of reduced field strength 1 T

Basic Surgical Techniques in the Göttingen Minipig: Intubation, Bladder Catheterization, Femoral Vessel Catheterization, and Transcardial Perfusion

The emergence of the Göttingen minipig in research of topics such as neuroscience, toxicology, diabetes, obesity, and experimental surgery reflects the close resemblance of these animals to human anatomy and physiology 1-6.The size of the Göttingen minipig permits the use of surgical equipment and advanced imaging modalities similar to those used in humans 6-8. The aim of this instructional video is to increase the awareness on the value of minipigs in biomedical research, by demonstrating how to perform tracheal intubation, transurethral bladder catheterization, femoral artery and vein catheterization, as well as transcardial perfusion